by
vtmnldy
on Wed 03 Aug 2005 11:32 AM CDT
The University of Virginia recently published a study in the New England Journal of Medicine stating that Echinacea did not prevent or treat colds.
Frustrating isn't an adequate word for the effect these poorly designed studies have on health professionals, and this one is another clone in the line "How to prove a nutraceutical doesn't work"!
1. The researchers wrote: "it is conceivable that other chemicals in echinacea are important." The study only used one plant, Echinacea augustifolia. Many commercial preparations also use Echinacea augustifolia and Echinacea purpurea. The researchers wrote: "Given the great variety of echinacea preparations, it will be difficult to provide conclusive evidence that echinacea has no role in the treatment of the common cold." (Well, that tells us what they are out to do, doesn't it??)
2. The researchers wrote: "It is possible, although unlikely, that echinacea works on other respiratory viruses." The study used one of 300 known cold and respiratory viruses. According to a New York Times article, July 28, 2005, Study Says Echinacea Has No Effect on Colds by Gina Kolata : "one of the study's authors, Dr. Rudolf Bauer, agreed that the study should be repeated with other echinacea species, preparations and doses."
3. The World Health Organization has endorsed echinacea as a treatment for the common cold.
4. The dosage in the study was the equivalent of 900 milligrams of dried echinacea root per day, which is 330 percent lower than the three grams that is commonly used commercially and recommended by organizations such as the World Health Organization (WHO) and the Canadian Natural Health Products Directorate.
5. As reported in Len Monheit's editorial at www.npicenter.com, According to Dr. Michael Murray, the Director of Education for Factors Group of Nutritional Companies, "What determines the effectiveness of any herbal product is its ability to deliver an effective dosage of active compounds. The specific components of echinacea responsible for its immune-enhancing effects are the polysaccharides, alkylamides and the cichoric acid. While each of these components is effective alone, the greatest degree of effectiveness occurs when the three active components are combined and at a specific ratio." None of the three extracts used on the 399 study participants actually contained all of the three necessary compounds.
Poor old echinacea! It may be the victim of dirty tricks, but it's still in my repertoire of effective remedies.