I have been waiting for this shoe to drop.  It stands to reason you can't permanently suppress stomach acid (particularly when you consider that all too frequently this is the OPPOSITE of what actually needs to be done - see my article on Digestion here) without having to pay a price.

And here we have it:  a new, more virulent strain of a nasty bacterium called Clostridium difficile (C. diff for short) is becoming strangely common in patients who have been taking Zantac, Prilosec, Nexium, Pepcid and other heartburn medications of that ilk. Would you trade heartburn relief for diarrhea, vomiting, infection of the lining of the colon, and possibly deadly illness?

Consider instead Vitamin Research Products' Cease Fire

Heartburn medications raise risk for C. Diff

This is a most intriguing study.  B6 is a fascinating nutrient, involved as it is in almost every metabolic function. It is easily depleted through use of alcohol and drugs, medicinal or other, and also high consumption of simple sugars.

Add to that the catch-22 loop that not only is B6 essential for the production of Hydrochloric Acid, but B6 also needs HCL to be absorbed, and you can see that  deficiencies are going to be common. In fact, using the P-5-P form of B6, which is more absorbable, is a strategy I highly recommend.

It has always stood to reason that B65 deficiencies are going to lead to trouble, since it is part of DNA synthesis, but this is the first study to actually document the process.

High daily intake of B6 cuts colon cancer risk by 58%