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Alpha Lipoc Acid is an antioxidant with many health benefits - I have a more detailed article on it here - it is widely used in diabetic problems, and to protect the liver. However, perhaps its most interesting ability is to regenerate our supplies of Vitamins C and E. Now comes some preliminary research showing it may help in Rheumatoid Arthritis. |
| "Alpha-lipoic acid suppresses the development of collagen-induced arthritis and protects against bone destruction in mice," Lee EY, Lee CK, et al, Rheumatology International, 2007; 27(3): 225-233. (Address: Division of Allergy and Rheumatology, Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, 388-1 Pungnap-Dong, Songpa-Gu, Seoul, 138-736, Republic of Korea. E-mail: byoo@amc.seoul.kr ). |
| In a study involving mice, alpha-lipoic acid was found to attenuate the development of collagen-induced arthritis (CIA) in a dose-dependent manner. The mice were divided into three groups. Group1 received alpha-lipoic acid (ALA) 10 mg/kg; Group2 received ALA 100 mg/kg; and Group3 received a placebo. Results found that mice treated with lipoic acid experienced a dose-dependent reduction in CIA. Furthermore, bone erosion and destructive changes were prevented with ALA administration in vivo, and formation of osteoclasts was inhibited in vitro. Levels of intracellular reactive oxygen species, and concentrations of TNF-alpha, IL-1 beta, IL-6, and synovial NF-kappa B binding were found to be markedly higher among mice with CIA as compared to controls; after treatment with alpha-lipoic acid, these levels decreased significantly. The authors of this study conclude, "…these results indicate that alpha-lipoic acid may be a new adjunctive therapy for rheumatoid arthritis." |
My selection of Alpha Lipoic Acid supplements
